SPECIALLY COLLECTED PAPERS
Shimadzu Review 78[3・4] (2021)
Abstract
Metabolomics is now used in drug discovery and various other fields, but due to increased number of analytes and improvements in equipment throughput, analyzing the enormous amounts of collected data has become a bottleneck in the analysis workflow. We have developed the Multi-omics Analysis Package (MAP) to support the analysis and interpretation of data. When analyzing enormous amounts of data, multiple software are needed to perform visualization, statistical analysis, and other tasks, but using multiple software requires formatting adjustments and other complex operations. By building a pipeline on the Garuda Platform that links software without the need for formatting adjustments, the MAP facilitates the creation of visualizations that mirror the results of statistical analyses and otherwise obtain analytical results. We have also created a visualization metabolic map for four method packages that are ready-to-use and allow users to perform analysis without considering analysis conditions. Using these method packages with the MAP and their metabolic maps should allow even novice metabolomics researchers to analyze, process, and visualize data without needing to consider conditions and parameters, thereby making data interpretation easier.
1AI Solution Unit, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan
2MS Business Unit, Life Science Business Department, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
3IT Solutions Unit, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
4Global Marketing Department, Analytical & Measuring Instruments Division, Shimadzu Corporation, Tokyo, Japan
5Cell Business Development Section, Life Science Business Department, Analytical & Measuring Instruments Division, Shimadzu Corporation, Tokyo, Japan
6The Systems Biology Institute, Tokyo, Japan
7Graduate School of Information Science and Technology, Osaka University, Osaka, Japan
8Osaka University and Shimadzu Omics Innovation Research Laboratory, Osaka University, Osaka, Japan
9Graduate School of Engineering, Osaka University, Osaka, Japan
10Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan
11Life Science Business Department, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
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