Analysis of Per-and Polyfluoroalkyl Substances (PFAS) using the LCMS-8050 Triple Quadrupole Mass Spectrometer According to EPA Draft Method 1633

User Benefits

- Limits of Quantitation listed in EPA Draft 1633 were readily achieved with the Shimadzu LCMS-8050, a system that delivers high-quality data, throughput, and affordability. - The robust LCMS-8050 performs well with complex environmental matrices, such as wastewater samples used in this study. - This efficient instrument is field upgradeable to higher sensitivity instruments, which makes it a versatile and future-proof solution for PFAS analysis.

Introduction

This application note demonstrates that the Shimadzu LCMS-8050 meets and exceeds the Quality Assurance and Quality Control criteria and performance specified in Environmental Protection Agency (EPA) draft method 1633 for the analysis of Per- and Polyfluoroalkyl Substances (PFAS) in environmental samples. All analytes were reliably quantitated at or less than the Limit of Quantitation (LOQ) reported in the EPA draft method. This work proves the suitability of the Shimadzu LCMS-8050 for accurate and robust analysis of PFAS in routine laboratories in accordance with present demands in sensitivity and throughput. The method presented here can be optimized for other matrices or additional compounds.

14 de enero de 2024 GMT