Metabolite Analysis by Muscle Measuring System and GC/MS

User Benefits

－ Volcano plot results can identify significant differences in metabolic pathway positions. － A multi-omics analysis package can detect digital biomarkers with a large number of features, using both primary metabolite and muscle strength measurement data.

Introduction

Frailty (muscle weakness) is a condition that falls between the healthy state and the care-requiring state. It is associated with physical and cognitive decline and is more likely to affect older people. This condition affects 8.7% of the elderly in Japan and 5% in the United States, significantly impacting medical insurance in each country ^{1), 2)}. However, muscle strength measurement alone cannot infer and study the causes of muscle weakness and cannot provide enough information to prevent or improve frailty. Metabolite measurements are important better to understand the mechanism and progress of muscle weakness. For example, muscle weakness can cause an imbalance in metabolites. Specific approaches to prevent or improve frailty can be explored using metabolite measurements. In addition, metabolite measurements are essential to evaluate the therapeutic effects of frailty. By tracking changes in metabolites and muscle strength, doctors can more accurately assess the effects of treatment and prognosis. For example, if an increase in a particular metabolite indicates treatment efficacy, the treatment plan can be adjusted based on the measurement of that metabolite.

2 de abril de 2024 GMT