Analysis of Epichlorohydrin in Water using HS GC/MS

User Benefits

- Water samples can be analyzed with a simple preparation. - Using a headspace autosampler, the analysis of epichlorohydrin in water quality can be performed conveniently.

Introduction

Epichlorohydrin (ECH) is primarily used in the production of various resins (epoxy, ion exchange, etc.) and synthetic glycerin. Additionally, it is used as a stabilizer for carbon containing products in surfactants, plasticizers, dyes, and pharmaceuticals). Some studies have demonstrated that damage to the nasal passages, respiratory tract and kidneys occurred in rodents exposed to epichlorohydrin. It has been observed that exposure to ECH induced a high nasal cancer response in rats, therefore, the United States Environmental Protection Agency (EPA) has classified epichlorohydrin as a “probable” human carcinogen. According Water Pollutants of Water Environment Conservation Act, the permissible discharge limits of ECH in water were 0.03 to 0.3 mg/L by the classified area. The test method for ECH analysis in water is "Epichlorohydrin-Solvent Extraction/Gas Chromatography-Mass Spectrometry (ES 04608.1)" as the official test method of water pollution. The ES 04608.1 was used to extraction method with a large volume of solvent, it caused high consumption of solvent and long time of preparation. To solve these disadvantages, analysis of ECH in water in this application was performed using HS-20 NX headspace sampler without sample pretreatment. This application demonstrates the validation of a method for analysis of ECH in water samples using HS-GC/MS to meet the demanded levels of ES 04608.1 in Korea.

19 de septiembre de 2024 GMT