Analysis of Diethylene Glycol in Glycerin Using Brevis™GC-2050

User Benefits

- The compact Brevis GC-2050 allows for high-throughput analysis by increasing the number of operational units in the lab. - Despite its small size, the Brevis GC-2050 achieves uncompromised analytical performance, enabling the analysis of concentrated glycerin in compliance with pharmacopeial standards.

Introduction

In response to the issue of contamination in pharmaceuticals and toothpaste with diethylene glycol, certain parts of the Japanese Pharmacopoeia were revised through Ministry of Health, Labour and Welfare Notification No. 32 (February 21, 2008). In Application News G259 “Analysis of Diethylene Glycol in Glycerin,” a measurement example conforming to the pharmacopoeial requirements is introduced using GC-2010. While each country has its own official methods, this application conducted measurements on a Brevis GC-2050 under conditions where the Split/Splitless injection unit (SPL) temperature was set higher, taking into consideration that the sample component has a high boiling point, with reference to the Japanese Pharmacopoeia.

November 26, 2024 GMT