Rapid Screening of Illegally Added Drugs in Health Food Product by DPiMS-8060

User Benefits

- Based on PESI ionization technology, the simplified pretreatment and micro sampling are suitable for precious samples and reduce mass spectrometry contamination. - With a peak collection rate of up to 3 peaks per second, high-sensitivity rapid screening of 98 drugs (196 MRM channels) can be completed within 2.0 minutes.

Introduction

Health food refers to food with specific health functions. Criminals usually add illegal additives that can produce effects similar to prescription drugs in health foods, enhance the efficacy of health products, and make huge profits. It is necessary to establish a rapid detection method for illegal additives in health food. In this Application News , a rapid analytical method for the determination of several illegally added drugs(β-receptor agonists, weight loss drugs, antihypertensive drugs, lipid-lowering drugs, aphrodisiacs, antianxiety drugs) in health food was established using a probe electrospray ionization (PESI) mass spectrometer DPiMS-8060. The Principle behind the PESI Method was shown in this article. This method can complete rapid qualitative screening of 98 illegally added drugs within 2.0 minutes. The sensitivity and precision of the method were evaluated, and the detection limits were 0.02-10 ng/mL; The detection precision RSDs of all drugs were within 10%; Using commercially available oral liquids for a matrix spiked test, the target substances can be detected in the spiked samples. This method is fast, accurate, and highly sensitive, suitable for rapid qualitative screening of illegally added drugs in health food.

23 de diciembre de 2024 GMT