Learning Portal

2023-09-05

This presentation will provide advice for routine HPLC analysis. This time we will look at baseline fluctuations and problems in reproducibility.

2023-09-05

This presentation will provide advice for routine HPLC analysis. Today, I’ll be talking about abnormal peak shape, particularly the effect of the sample solvent, mobile phase, column temperature and detector response.

2023-05-22

These are the most likely causes for abnormal peak shape. e.g.: Column degradation/ Effect of sample solvent/ Effect of mobile phase composition/ Temperature distribution in analytical column/ Effect of filtration setting in detector We talk about countermeasures for these while showing respective examples.

2023-02-07

Here are some basic considerations on LC/MS analysis. It is for beginners who are going to perform LC/MS analysis.

2022-06-28

Now easily integratable into liquid chromatograph systems, mass spectrometry (MS) is increasingly recognized as an orthogonal detector that adds extra information to UV-based photodiode array (PDA) detectors. Analysis of chemical compositions and/or impurities is a typical application employing both PDA and MS detectors for enriching the information obtained from a single analysis.

2022-06-28

Now easily integratable into liquid chromatograph systems, mass spectrometry (MS) is increasingly recognized as an orthogonal detector that adds extra information to UV-based photodiode array (PDA) detectors. Analysis of chemical compositions and/or impurities is a typical application employing both PDA and MS detectors for enriching the information obtained from a single analysis.

2017-12-12

The determination of water content in alcoholic beverages, solvents and various consumer products such as foods, fuels, pharmaceuticals, and petroleum products is one of the most common types of chemical testing. Many techniques such as gravimetric analysis, gas chromatography (GC), Karl Fischer Titration, near infra-red spectroscopy, and others have been used for water quantification with good results. [1] However, the limitations of these approaches can include high limits of detection, large sample sizes required for trace analysis, side reactions, the use of expensive consumables, and the production of chemical waste. Previous work by Prof. Daniel Armstrong and co-workers has described the use of ionic liquid GC capillary columns for the trace analysis of the water content in a wide variety of solvents. [2] These columns were capable of providing a rapid and quantitative determination of water contents using very small sample amounts. This webinar further examines the characteristics of ionic liquid capillary columns for the GC analysis of water.

2024-09-20

In this webinar, we will explore how Shimadzu’s latest GC-MS instruments, in combination with the multi-platform software LabSolutions and LabSolutions Insight, enable successful detection, quantitation, and suspect screening of VOCs and SVOCs. Plus, discover how these tools support EPA methods, from initial sample analysis to final data reporting.

2024-09-20

In this webinar, we will explore how Shimadzu’s latest GC-MS instruments, in combination with the multi-platform software LabSolutions and LabSolutions Insight, enable successful detection, quantitation, and suspect screening of VOCs and SVOCs. Plus, discover how these tools support EPA methods, from initial sample analysis to final data reporting.

2022-03-03

1. Short introduction to TOC 2. Different standardization 3. Standard and sample preparation 4. What can affect on the results