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Differences in the selectivity of reversed-phase columns
Columns for reversed-phase chromatography are developed and sold by various column manufacturers. The separation behavior of the target compound may vary greatly depending on the column brand or series, even if the functional group is the same.
Shimadzu has released the Shim-pack Mix-HILIC, Chromatography Column for Hydrophilic Interactions
Comprehensive Analysis of Hydrophilic Metabolites in Metabolomics