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Autosampler

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Nexera Series

SIL-30AC

SIL-30AC Autosampler

The total-volume injection SIL-30AC autosampler features a pressure tolerance of 130 MPa as well as the world’s fastest sample injection (10 seconds), which dramatically reduces the total cycle time. It includes auto pretreatment and overlapping functions as standard, and an optional loop-injection method configuration to minimize delay volume. With reduction of the needle contact area, special coatings, surface treatments, and a new needle seal, the SIL-30AC reaches a new level of low carryover performance, which is especially beneficial for LCMSMS analysis. In addition, the included sample cooler features a dehumidifier function for storing samples at a constant temperature between 4°C and 40°C.

Rackchanger II and SIL-30AC Autosampler

The rackchanger unit replaces the microplates on autosampler racks to enable samples to be continuously analyzed . It allows loading up to 12 microplates inside the unit (maximum 4608 samples). Samples can be temperature-controlled with a block heating/cooling system (with dehumidifier function and 4 °C to 40 °C range) not only to refrigerated temperatures, but also to stable temperature levels near room temperature.

Method Variable sample injection volume and total volume direct injection
Allowable Operating Pressure 66 MPa
Injection Volume Range 0.1 µL to 50 µL (0.1 µL to 100 µL with option)
Number of Samples Processed 175 (1-mL vials), 105 (1.5-mL vials, 70 for 20AC), 50 (4-mL vials), 192 (two 96-well MTP/DWP), 768 (two 384-well MTP/DWP) Besides these, ten 1.5-mL vials can be used
Injection Volume Precision Max RSD 0.3 % (normally max 0.2 %: depending on specified conditions)
Cross-Contamination Max 0.005 % (depending on specified conditions, without rinsing, normally max 0.0035 %)
Needle Rinsing Freely settable, before or after sample injection
Operational Temp. Range 4 - 35 °C

Prominence Series
SIL-20A/20AC Autosampler

SIL-20A

The SIL-20A is a total volume injection type (direct injection) autosampler that enables high-speed injection and multi-analyte processing. Materials used in needle, valve, and other flow lines were closely considered and a needle rinsing function is provided to carefully minimize cross-contamination (carryover), which is especially useful for high-precision LC-MSMS analysis. The SIL-20AC includes a sample cooler that features a dehumidifier function for storing samples at a constant temperature between 4 °C and 40 °C.

Rack Changer

The rackchanger unit exchanges the microplates on autosampler racks to enable samples to be continuously analyzed. 12 plates can be mounted inside the main unit and stored under refrigerated conditions.

Method Variable sample injection volume and total volume direct injection
Injection Volume Range 0.1 µL to 100 µL (0.1 µL to 2000 µL with option)
Number of Samples Processed 175 (1-mL vials), 105 (1.5-mL vials), 50 (4-mL vials), 192 (two 96-well MTP/DWP), 768 (two 384-well MTP/DWP)
*Twelve 96-well MTP/DWP in the rackchanger
Injection Volume Precision Max RSD 0.3 % (under specified conditions)
Cross-Contamination Max 0.005 % (naphthalene and chlorhexidine)
Needle Rinsing Freely settable, before or after sample injection

Comparison for Autosampler Selection Autosamplers can be selected according to objectives.

Model Name Features/Applications Injection Volume (µL) Number of Vials Microplate Capacity Main Liquid Contact Surface Materials
SIL-20A Outstanding reproducibility and accuracy for trace volume injection. A needle rinsing function is included standard to minimize cross-contamination (carryover). It also allows high speed injection. (direct injection, specialized needle coating, and PEEK rotor) 0.1 to 100 (max 2000) 175 (1 mL), 105/70 (1.5 mL), 50 (4 mL) Cools max two 96/384-well plates PEEK, (SS)

Manual Injectors
7725/7725i,
8125 (semi-micro),
9725/9725i (PEEK)
3725i (Preparative)

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