Nexera lite inert
High Performance Liquid Chromatograph
Inert High Performance Liquid Chromatograph (HPLC) System
The analysis of proteins such as antibody drugs requires careful operation because a high-salt mobile phase sometimes corrodes the system. In addition, the adsorption of proteins to metal surfaces often results in poor chromatographic performance.
Providing the same expandability and superior performance advantages of the Nexera series HPLC Systems, the Nexera lite inert is the ideal solution for addressing challenges related to metal-adsorption that compromise quantitative accuracy, sensitivity, or separation and mobile phases that cause system durability problems. It is a robust HPLC system that eliminates the risk of corrosion by high-salt mobile phases and sample adsorption onto metal surfaces with a maximum pressure tolerance of 20 MPa. It also improves the data quality of protein analysis in biological samples with superior reproducibility, without any special considerations for stable and long-term use.
Features
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Aggregates of antibody drugs show immunogenicity and cause a decrease in the purification efficiency and production. Therefore, an aggregation test is one of the most critical evaluations when manufacturing biopharmaceuticals and controlling their quality.
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Nexera lite inert provides good repeatability of retention time because the solvent delivery unit LC-40i of Nexera lite inert can deliver mobile phases accurately.
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The pH Monitor, pHM-40, continuously monitors and records the pH of the mobile phase. The pH and detector chromatograms are saved within the same data file and can be overlapped, ensuring efficient data traceability.
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Downloads
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Applications
Documents | Date Creation Date |
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2024-05-14 | |
2024-02-27 | |
2023-09-26 |
News / Events
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New Method Development System
LabSolutions™ MD improves method development efficiency by taking an Analytical Quality by Design (AQbD) approach. This software efficiently develops highly reliable analysis methods by configuring mobile phases, columns, and other parameters using an analysis function that automatically generates analysis schedules with the experimental design method and a data analysis function that plots a design space and predicted chromatogram.
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New Nexera Prep Preparative Purification Liquid Chromatograph
The Nexera™ Prep Purification System provides optimal solutions for your laboratory needs.
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Shimadzu has released the Shim-vial™ H glass, S glass.
Shimadzu provides high-quality vials that thoroughly eliminate these risks by visually inspecting each vial, allowing them to be used with confidence.
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Shimadzu has released the MUP-3100, Fully Automated Sample Preparation Module for Glycan Analysis
Shimadzu developed the MUP-3100 Fully Automated Sample Preparation Module for Glycan Analysis in conjunction with Sumitomo Bakelite Co., Ltd., for use with their antibody N-glycan analysis kit. The MUP-3100 eliminates manual sample preparation, increases overall analysis throughput, and improves reproducibility.
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Ion Chromatography Solutions for Environmental Analysis
Shimadzu has focused on the development of instruments for environmental analysis for decades, helping scientists to detect, identify and quantify trace-level pollutants and meet environmental testing demands, for both regulatory purposes and to advance Research & Development.
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Shimadzu has released the Peakintelligence™ for LC
Liquid chromatography is now an indispensable analytical technique used in pharmaceutical, food, and a wide variety of other industries. In these industries, there is a need for efficient data analysis methods that are not user-dependent. Peakintelligence for LC software includes AI algorithm* that was developed by learning expert peak integration skills.