Research Areas
Brain and Mind
Contributing to prevention and treatment of root causes of
brain-related disorders by visualizing the brain and mind status
![Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry:Technology used to ionize and analyze the masses of macromolecule/polymer compounds without damaging them [MS]](/research_and_development/kyolabs/img/field/brain/product01.png)
![Functional Near-Infrared Spectroscopy Imaging:Technology used to visualize brain activity status by measuring changes in blood flow at the brain surface [fNIRS]](/research_and_development/kyolabs/img/field/brain/product02.png)
![Liquid Chromatograph Mass Spectrometry:Technology used to separate components in liquid samples and ionize them to analyze their masses [LC-MS]](/research_and_development/kyolabs/img/field/brain/product03.png)
Dementia
Establishing testing and diagnostic methods
Estimating Amyloid-Beta Accumulation Levels in the Brain
Joint research with the National Center for Geriatrics and Gerontology
Discovering biomarkers that can be used to measure amyloid beta accumulation levels in the blood, which have been linked to the progression of Alzheimer’s disease
- Stages leading to Alzheimer’s Disease
- PET examination
-
Observation of accumulated areas 
- Screening with Blood Biomarkers
-
Simple screening
(minimally invasive and low cost)
- With no
amyloid beta
accumulation 
- With
amyloid beta
accumulation 
Simple Measurement of Risk for Mild Cognitive Impairment (MCI)
Joint research with Sochikai Memory Clinic
Measuring changes in brain blood flow during calculation task, etc
- Calculation task
- Such as successively subtracting 7 from 100
- Palm sensitivity task
- Differentiating similar letters drawn on the palm
Rehabilitation
Restoring brain function
Promoting the restoration of brain function during rehabilitation by having patients imagine body movement while checking changes in brain blood flow for themselves
Joint research with Kawasaki Medical School
- Neurofeedback
- Training to simulate brain areas with cognitive decline
Depression
Improving accuracy of testing and diagnosis
Predicting Risk of Depressio
Joint research with Kyushu University
Identifying risks of developing depression at an early stage by measuring metabolites in blood
