Pyrolysis/Thermal Desorption -GC/MS for Deterioration Markers of Chemical Products

User Benefits

－ Scan data can be deconvoluted and annotated with NIST and Shimadzu libraries on AnalyzerPro XD. － Multivariate analysis and machine learning can be performed on eMSTAT Solution by loading the annotated scan data from AnalyzerPro XD.

Introduction

In modern life, many people are exposed to synthetic polymer products. Among them, polymer products for medical devices such as artificial joints and cardiac pacemakers are important items to support the life of users. However, due to long-term use and environmental effects, synthetic polymer products can deteriorate, and this deterioration is difficult to determine by color, shape, etc., thus requiring accurate objective measurements. For example, if the material of a synthetic polymer product deteriorates, the synthetic polymer product may release harmful chemicals. These substances can have adverse effects on the human body and can have adverse health effects. In addition, by investigating the mechanism and cause of deterioration in detail, you can find countermeasures and improvement measures to improve the durability and life of the product. This will make your product more competitive in the market. A gas chromatograph mass spectrometer is useful for objectively assessing the degree of deterioration of chemical products such as synthetic polymer products. In this report, we performed deconvolution and annotation using the GCMS-QP2020 NX equipped with a pyrolyser EGA/PY-3030D (Frontier Labs, Inc.), and AnalyzerPro XD, which eliminates the cumbersome task of identifying all peaks by conventional visual inspection (Fig. 1). The annotation results were imported into eMSTAT Solution™ for PLS-DA analysis to create a list of differentiating compounds. We introduce an appropriate and efficient GC/MS measurement and analysis workflow to help you manufacture and develop safe synthetic polymer products.

March 26, 2024 GMT