Quantitative Analysis (Mass Spectrometer)-Oligonucleotide Therapeutics
After chemical synthesis, the unrefined oligonucleotide therapeutics are purified to remove impurities and recover a high-purity target substance. It is essential that the target substance is checked and impurities detected and identified to verify the safety and efficacy of the drugs.
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The LCMS-TQ RZ series triple quadrupole mass spectrometers are designed to offer the three “Rs” of reliability, resilience, and responsibility. The series offers improved safety and provides worry-free analytical solutions to ensure that highly reliable data can be acquired.
LCMS-9050
Quadrupole Time-of-Flight Liquid Chromatograph Mass Spectrometer
This quadrupole time-of-flight (Q-TOF) mass spectrometer offers the highest class of mass accuracy reliability. Shimadzu’s unique high-precision temperature control system suppresses even tiny mass variations caused by external factors, ensuring accurate mass measurements without the operator worrying about mass calibration. Insight Biologics oligonucleic acid sequencing software can identify oligonucleic acid impurities and confirm sequences with predicted modification positions.