LA-ICP-MS
Laser ablation-inductively coupled plasma-mass spectroscopy
Various applications of mass spectrometry imaging (MS imaging) using laser ablation-inductively coupled plasma-mass spectroscopy (LA-ICP-MS) as a method for imaging metals in living organisms have been reported in recent years.
The main advantage of LA-ICP-MS imaging is that it can efficiently ionize a variety of elements present on the tissue surface at once, providing high quantitation over a wide dynamic range. The data output from the LA-ICP-MS software can be used for analysis and imaging of thin-film samples. Data output from the LA-ICP-MS software can be read directly into the Shimadzu MS imaging data analysis software IMAGEREVEAL MS for easy analysis.
LA-ICP-MS Software
Batch registration of line scan information
The sample information can be entered using the image of the irradiation area (Number of lines x irradiation time) set by the laser ablation instrument. Reduce the time and effort required to enter information to 1/10 or less*.
*When 10 or more lines are registered
Data output per sample
The acquired data is output as one data file per sample. Prevents missing or mixed data when multiple line data are selected and output.
Supports imdx format
The data of the output imdx format can be read as it is by Shimazu Mass Spectrometry Imaging Data Analysis Software IMAGEREVEAL™ MS. You can start the analysis immediately without converting the data.
Sample Information Input Method Specialized for Imaging
Batch registration of line scan information
LA-ICP-MS imaging is a collection of laser irradiation lines. In the past, information for each line had to be entered into the ICP-MS. “LA-ICP-MS Software” uses a 1-sample input method to reduce the time and effort required to input information. You can enter up to 10,000 lines of information on just 1 line.
Data output per sample
In order to analyze the imaging data, it is necessary to output the data for each sample. The Shimadzu LA-ICP-MS Software outputs one data file each time the measurement of one sample is completed. Unlike conventional software, it is not necessary to select and output line data after measurement. Measurement information is also included in the data file, making it easier to manage the data and preventing human error such as mixing of data measured under different conditions.
Main Window
Mass Spectrometry Imaging Data Analysis Software IMAGEREVEAL MS
Supports imdx format
Since the data is output in the data format imdx of Mass Spectrometry Imaging Data Analysis Software IMAGEREVEAL MS, it can be opened directly by IMAGEREVEAL MS and the analysis work can be started immediately. You don't need to convert data or create your own software to read data. It is also easy to combine the organic images of the MALDI TOF MS and iMScope series with the inorganic images of the LA-ICP-MS.
▼ Multimodal Imaging System
Multimodal Imaging System
MALDI-MS molecular imaging data and LA-ICP-MS elemental imaging data can be analyzed using a single software solution. That makes multimodal imaging more accessible.
News / Events
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What is ICP-MS (Inductively Coupled Plasma Mass Spectrometry)?
Basics of Inductively Coupled Plasma Mass Spectrometry is now available.
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Three Analytical and Measuring Instruments Win the Internationally Recognized “iF Design Award 2024”
The Shimadzu LCMS-2050 high-performance liquid chromatograph mass spectrometer, the Brevis GC-2050 gas chromatograph, and the ICPMS-2040/2050 ICP mass spectrometer won the internationally recognized iF Design Award 2024 in the product design category.
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New Video: The Cabbage Core, Trash or Treasure?
Most people throw out the cabbage core when cooking, but is the core really just trash or actually a hidden treasure of nutrients?
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New Video: ICPMS-2040/2050 Extended Rinsing
The extended rinsing function automatically performs an additional rinse sequence when a target element exceeds a predetermined upper limit. A second rinse solution can be used in the additional rinsing sequence to improve rinsing effectiveness. Consequently, carryover is eliminated to ensure high-quality data.
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New Video: ICPMS-2040/2050 ProActive Rinsing
ProActive Rinsing can shorten the analysis time by sharting the rinsing sequence in advance. While measuring multiple samples, the rinsing sequence can be started early by sending the autosampler probe to rinse while collecting data using sample already in the suction line. This greatly reduces measurement time and conserves sample.
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Shimadzu has released the ICPMS-2040 Series / ICPMS-2050 Series, Inductively Coupled Plasma Mass Spectrometry
ICPMS-2040/ 2050 Series has achieved a harmonious blend of environmental-friendliness and analytical performance.