iMLayer
iMScope QT - Options
Imaging Mass Microscope
Imaging Mass Microscope
With mass spectrometry imaging (MSI), suitable pretreatment is important. High quality MSI analysis results are obtained from a combination of the spray method and the vapor deposition method.
Automatic Sprayer
iMLayer AERO (Option)
The iMLayer AERO incorporates a sample stage that moves at a controlled rate while maintaining the same distance from the spray nozzle, enabling stable matrix spraying. Over multiple strokes, the sample becomes laminated with fine matrix crystals, enabling high sensitivity and high spatial resolution.
Imaging with High Reproducibility
Humidity Control
Humidity does not impact matrix deposition because the atmosphere within the spray chamber is replaced before pretreatment. Spraying can be performed under more stable conditions than with a hand spray.
Clog-Free Reagent Delivery
If the matrix clogs the nozzle tip, the spray becomes unstable, which can lead to lower reproducibility. The rinsing mechanism allows for clog-free stable spraying which enables high reproducibility in MALDI analyses.
Matrix Vapor Deposition System
iMLayer (Option)
Applying the matrix by the vapor deposition method supports high resolution MALDI imaging.
Both Spatial Resolution and Sensitivity Thanks to the Two-Step Vapor Deposition Method
Two-Step Vapor Deposition
iA two-step vapor deposition method has been developed*, which provides high spatial resolution (5 to 10 μm) and high sensitivity, thanks to a combination of iMLayer (vapor deposition method) and iMLayer AERO (spray method). This unique experiment can only be implemented using Shimadzu sample preparation solutions.
* Patent No.: JP6153139 and JP6183779
IMAGEREVEAL™ MS
Mass spectrometry imaging data analysis software
Automatically uncover important information from large amounts of data with IMAGEREVEAL MS.