Discover the Optimal LC-MS: Explore Shimadzu's Innovations and Analytical Solutions
History of Technological Advancements
Shimadzu boasts a long history of contributing to society through the development of innovative technologies and products. Today, with over a half-century of history developing mass spectrometry technology, Shimadzu remains committed to contributing to society through science and technology in the future.
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Beginning of Shimadzu Foundation and Business ExpansionGenzo Shimadzu, Senior established a business manufacturing physics and chemistry instruments. That marks the beginning of Shimadzu’s history. Later, from 1894 to 1916, Genzo Shimadzu, Junior expanded the business by taking on the challenge of entering new fields, such as storage batteries, medical X-ray systems, and eventually analytical instruments. |
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Early Period of Mass Spectrometry LKB-9000Shimadzu released the world’s first mass-produced GC-MS (magnetic sector type) system in partnership with LKB of Sweden. The basic concept of that instrument was later used to design Shimadzu GC-MS and LC-MS systems. |
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 LCMS-QP1000Shimadzu released its first thermospray-based LC-MS product. Thermospray became the most popular interface for LC-MS systems in the 1990s. |
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 LCMS-2010Shimadzu redesigned the lens system, spray unit, and other portions of previous LC-MS systems using unique Shimadzu technologies to offer the LCMS-2010 single quadrupole mass spectrometer that provided over 10 times higher sensitivity than earlier models. |
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 LCMS-2020The ultra fast LCMS-2020 supported ultra fast LC. The single quadrupole mass spectrometer was equipped with Shimadzu’s proprietary UF Technologies that enabled dramatic improvements in both speed and sensitivity. |
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Taking on the Challenge of Triple Quadrupole Mass Spectrometry LCMS-8030Shimadzu released the LCMS-8030 as Japan’s first triple quadrupole mass spectrometer. At the time, it achieved the world’s fastest detection speed, satisfying the need to measure huge numbers of samples when analyzing pollutants in water and soil, drug metabolites, residual pesticides in foods, and so on. |
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 LCMS-8060After releasing the LCMS-8050 (in 2013), the LCMS-8060 was released as Shimadzu's high-end triple quadrupole model. The LCMS-8060 featured additional ion path improvements from the LCMS-8050 that achieved about three times higher sensitivity. |
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 LCMS-9030Shimadzu released the LCMS-9030, Shimadzu’s first quadrupole time-of-flight mass spectrometer, in the market for high resolution accurate mass (HRAM) analysis. The system featured technology that provided simple operation together with high accuracy, sensitivity, and resolution that allowed highly reliable accurate mass measurement capabilities for everyday use. |
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 LCMS-2050This compact model has a footprint that is 66 % smaller than the previous model, while simultaneously expanding the mass measurement range and achieving outstanding basic performance capabilities, such as fast positive-negative ion switching. |
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 LCMS-9050Proprietary power supply and data correction technologies enable simultaneous positive and negative ion measurements, which is difficult to achieve using a quadrupole time-of-flight mass spectrometer. That results in efficient acquisition of vast amounts of highly reliable data for developing increasingly advanced drugs and materials. |
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 OAD-TOF systemThis unique system from Shimadzu consists of an LCMS-9050 quadrupole time-of-flight mass spectrometer, which achieves simultaneous positive and negative ion measurements, equipped with the world’s first OAD ion dissociation technology. It can help analyze the structures of unknown components by determining the position of double bonds, which was difficult to do previously. |
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 LCMS-TQ RX SeriesImprovements to the nozzle shape used to spray samples increases analytical data reliability by achieving a more uniform spray. And, by efficiently injecting only ions into the mass spectrometer unit, the systems achieve high measurement sensitivity and robustness. |
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