All sample processing, from introduction, separation and concentration of target compounds, desalting and solvent replacement, to transfer to the LC-MS, has been completely automated.
Co-Sense for LC-MS
Liquid Chromatograph with online Sample Preparation
![Co-Sense for LC-MS](/an/sites/shimadzu.com.an/files/d7/ckeditor/an/qn504200000070d7-img/resize19-4-1.png)
In LC-MS, there are various factors which may preclude the applicability of HPLC with MS analysis, including the interference associated with non-volatile buffers often used in HPLC. Therefore, tedious procedures are adopted, in which separation and collection is conducted by HPLC, and after desalting and other processing, MS measurement is performed.
Co-Sense for LC-MS automates the entire process of separating and purifying the target compounds from the sample, including the processes of purifying, concentrating and desalting. This eliminates the need to select HPLC mobile phases to accommodate subsequent measurement using LC-MS.
Features
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Fully Automated Sample Processing
All sample processing, from introduction, separation and concentration of target compounds, desalting and solvent replacement, to transfer to the LC-MS, has been completely automated.
News / Events
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Ion Chromatography Solutions for Environmental Analysis
Shimadzu has focused on the development of instruments for environmental analysis for decades, helping scientists to detect, identify and quantify trace-level pollutants and meet environmental testing demands, for both regulatory purposes and to advance Research & Development.
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Shimadzu has released the Peakintelligenceā¢ for LC
Liquid chromatography is now an indispensable analytical technique used in pharmaceutical, food, and a wide variety of other industries. In these industries, there is a need for efficient data analysis methods that are not user-dependent. Peakintelligence for LC software includes AI algorithm* that was developed by learning expert peak integration skills.
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Oxygen heterocyclic compounds profile evaluation in cold-pressed Citrus essential oils using supercritical fluid chromatography coupled to photodiode array detector
A large number of analytical techniques to characterize the non-volatile composition of Citrus essential oils (EOs) were introduced in the literature. However, the reports of Citrus EOs analysis by supercritical fluid chromatography (SFC) with UV or mass spectrometry detectors for the analysis of non-volatile polar compounds are still few.
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Shimadzu has released the Shim-pack Mix-HILIC, Chromatography Column for Hydrophilic Interactions
Comprehensive Analysis of Hydrophilic Metabolites in Metabolomics
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A new video has been released -Finding Out What Makes Things Sour-
Ever wondered what makes some foods sour? In this video we explore that question while also introducing one of Japan's traditional sour foods!
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New Nexera FV
Nexera FV and LabSolutionsā¢ FV together form a new UHPLC system capable of monitoring flow synthesis and batch synthesis reactions, and automating formulation dissolution testing.