Achievements
  • Presentations at Conferences
  • Publication
2024.08

Novel mimetic tissue standards for precise quantitative mass spectrometry imaging of drug and neurotransmitter concentrations in rat brain tissues

Anal Bioanal Chem.

  • Kenichi Watanabe1
  • Sayo Takayama1
  • Toichiro Yamada1
  • Masayo Hashimoto1
  • Jun Tadano2
  • Tetsuya Nakagawa2
  • Takao Watanabe3
  • Eiichiro Fukusaki4,5,6
  • Izuru Miyawaki1
  • Shuichi Shimma4,5,6
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2024.Sum.

REACH Project : For Strategic Development of Highly Skilled Human Resources through Academia-Industry Collaboration

Manufacturing & technology, 76 (3), 62-66, 2024

  • Daisuke Hiramaru
  • Junko Iida
  • Hiroaki Nakanishi
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2024.07

New insights into the characteristic flavor components of traditional sour beers such as Lambic and Flanders Red Ale beers

J Biosci Bioeng . 2024 Jul;138(1):54-62

  • Kyoya Onishi1
  • Masahiro Furuno1
  • Asuka Mori1
  • Eiichiro Fukusaki1,2,3
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2024.07

Characteristics of kopyor coconut (Cocos nucifera L.) using sensory analysis and metabolomics-based approach

J Biosci Bioeng. 2024 Jul;138(1):44-53

  • Mercy Bientri Yunindanova1,2
  • Sastia Prama Putri1,3
  • Hengky Novarianto5
  • Eiichiro Fukusaki1,3,4
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2024.07

Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food

Food Chem . 2024 Jul 15:446:138744

  • Marvin N. Imana
  • Danielle E. Haslamb d
  • Liming Liange f
  • Kai Guog
  • Kaumudi Joshipurae g
  • Cynthia M. Pérezh
  • Clary Clishi
  • Katherine L. Tuckerj
  • JoAnn E. Mansonc
  • Shilpa N. Bhupathirajub d
  • Eiichiro Fukusakia k l
  • Jessica Lasky-Sub
  • Sastia P. Putria l
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2024.06

Metabolomic characterization of monoclonal antibody-producing Chinese hamster lung (CHL)-YN cells in glucose-controlled serum-free fed-batch operation

Biotechnology and Bioengineering

  • Puriwat Sukwattananipaat1
  • Hirotaka Kuroda1,2,3
  • Noriko Yamano-Adachi1,4,5
  • Takeshi Omasa1,4,5
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2024.05

13C-metabolic flux analysis reveals metabolic rewiring in HL-60 neutrophil-like cells through differentiation and immune stimulation

Metab Eng Commun . 2024 May 27:18:e00239

  • Takeo Taniguchi1
  • Nobuyuki Okahashi1,2,3
  • Fumio Matsuda1,2,3
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2024.04

New insights into the characteristic flavor components of traditional sour beers such as Lambic and Flanders Red Ale beers

J Biosci Bioeng. 2024 Apr 22:S1389-1723(24)00111-7

  • Kyoya Onishi1
  • Masahiro Furuno1
  • Asuka Mori1
  • Eiichiro Fukusaki1,2,3
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2024.04

Identification and enzymatic properties of arginine decarboxylase from Aspergillus oryzae

Appl Environ Microbiol. 2024 Apr 16:e0029424

  • Yui Murakami1
  • Soichiro Ikuta2
  • Wakao Fukuda2
  • Naoki Akasaka1,3
  • Jun-Ichi Maruyama4,5
  • Shuichi Shinma6,7,8
  • Eiichiro Fukusaki6,7,8
  • Shinsuke Fujiwara1,2
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2024.03

Development of a Mass Spectrometry Imaging Method to Evaluate the Penetration of Moisturizing Components Coated on Surgical Gloves into Artificial Membranes

Mass Spectrom (Tokyo) . 2024;13(1):A0145

  • Erika Nagano1
  • Kazuki Odake1
  • Toru Akiyoshi2
  • Shuichi Shimma 1,3,4,5
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2024.03

Metabolome analysis of metabolic burden in Escherichia coli caused by overexpression of green fluorescent protein and delta-rhodopsin

J Biosci Bioeng. 2024 Mar;137(3):187-194.

  • Chinatsu Matsuyama1
  • Taisuke Seike1
  • Nobuyuki Okahashi1,2
  • Teppei Niide1
  • Kiyotaka Y. Hara3
  • Yoko Hirono-Hara4
  • Jun Ishii5
  • Hiroshi Shimizu1
  • Yoshihiro Toya1
  • Fumio Matsuda1,2
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2024.03

Rice grain structural characteristics of sake rice cultivar Hakutsurunishiki for daiginjo-shu brewing

Biosci Biotechnol Biochem. 2024 Mar 22;88(4):445-452

  • Yoshihiro Tamada1,2
  • Takuya Asai1
  • Takafumi Kubodera1
  • Takahiro Akashi1
  • Eiichiro Fukusaki2,3,4
  • Shuichi Shimma2,3,4
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2024.02

Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food

Food Chem. 2024 Feb 16:446:138744.

  • Marvin N. Imana 1
  • Danielle E. Haslamb d 1
  • Liming Liange f
  • Kai Guog
  • Kaumudi Joshipurae g
  • Cynthia M. Pérezh
  • Clary Clishi
  • Katherine L. Tuckerj
  • JoAnn E. Mansonc
  • Shilpa N. Bhupathirajub d 2
  • Eiichiro Fukusakia k l 2
  • Jessica Lasky-Sub 2
  • Sastia P. Putria l 2
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2024.01

A Bayesian approach for constituent estimation in nucleic acid mixture models

Front. Anal. Sci., 08 Jan 2024, 10.3389/frans.2023.1301602

  • Taichi Tomono1,2,3
  • Satoshi Hara1
  • Yusuke Nakai2
  • Kazuma Takahara2
  • Junko Iida3,4
  • Takashi Washio1
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2023.11

Applicability of supercritical fluid chromatography for oligonucleotide analysis: A proof-of-concept study

J Chromatogr A 1708(2023) 464333.

  • Momoka Hayashida1,2,3
  • Risa Suzuki3
  • Shinnosuke Horie2,3,4
  • Junichi Masuda3
  • Takao Yamaguchi1
  • Satoshi Obika1
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2023.10

Lipidome and metabolome analyses reveal metabolic alterations associated with MCF-7 apoptosis upon 4-hydroxytamoxifen treatment

Sci. Rep. (2023) 13:18549

  • Kazuki Nishimoto1
  • Nobuyuki Okahashi1,2,3
  • Masaharu Maruyama1
  • Yoshihiro Izumi4
  • Kohta Nakatani4
  • Yuki Ito2,5
  • Junko Iida2,5
  • Takeshi Bamba4
  • Fumio Matsuda1,2,3
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2023.02

Lipidome variation of industrial Saccharomyces cerevisiae strains analyzed by LC-QTOF/MS-based untargeted lipidomics

J Biosci Bioeng, 135(2) 102-108

  • Shuka Komori1
  • Nobuyuki Okahashi1 2 3
  • Junko Iida2 4
  • Fumio Matsuda1 2 3
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2022.07

Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform

Metabolites 2022, 12(7), 646

  • Nobuyuki Okahashi1 2 3
  • Yuki Yamada1
  • Junko Iida2 4
  • Fumio Matsuda1 2 3
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2022.01

Automated Recommendation of Research Keywords from PubMed That Suggest the Molecular Mechanism Associated with Biomarker Metabolites

Metabolites

  • Shinji Kanazawa 1,2,3
  • Satoshi Shimizu 1
  • Shigeki Kajihara 1
  • Norio Mukai 1
  • Junko Iida 1,2
  • Fumio Matsuda 3,4
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2021.05

Evaluation of change in metabolome caused by comprehensive diabetes treatment: A prospective observational study of diabetes inpatients with gas chromatography/mass spectrometry-based non-target metabolomic analysis

journal of diabetes investigation

  • Naohiro Taya 1
  • Naoto Katakami 1,2
  • Kazuo Omori 1
  • Shoya Arakawa 3
  • Shigero Hosoe 1
  • Hirotaka Watanabe 1
  • Mitsuyoshi Takahara 1,4
  • Kazuyuki Miyashita 1
  • Hitoshi Nishizawa 1
  • Taka-Aki Matsuoka 1
  • Masahiro Furuno 3
  • Takeshi Bamba 5
  • Junko Iida 6,7
  • Eiichiro Fukusaki 3
  • Iichiro Shimomura 1
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2021.02

Fake metabolomics chromatogram generation for facilitating deep learning of peak-picking neural networks

Journal of Bioscience and Bioengineering

  • Shinji Kanazawa 1,2,3
  • Akira Noda 1
  • Arisa Ito 2
  • Kyoko Hashimoto 2
  • Akihiro Kunisawa 1
  • Tsuyoshi Nakanishi 1
  • Shigeki Kajihara 1
  • Norio Mukai 1
  • Junko Iida 1,2
  • Eiichiro Fukusaki 4
  • Fumio Matsuda 3
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2019.08

Fragmentation of Dicarboxylic and Tricarboxylic Acids in the Krebs Cycle Using GC-EI-MS and GC-EI-MS/MS

Mass Spectrometry

  • Nobuyuki Okahashi 1
  • Shuichi Kawana 2
  • Junko Iida 2,3
  • Hiroshi Shimizu 1
  • Fumio Matsuda 1
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2018.09

Sugar phosphate analysis with baseline separation and soft ionization by gas chromatography-negative chemical ionization-mass spectrometry improves flux estimation of bidirectional reactions in cancer cells

Metabolic Engineering (2018)

  • Nobuyuki Okahashi 1
  • Kousuke Maeda 1
  • Shuichi Kawana 2
  • Junko Iida 2,3
  • Hiroshi Shimizu 1
  • Fumio Matsuda 1
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2018.08

FK960 binding proteins, quinone oxidoreductase2 and pyridoxal kinase were identified by LC-MS/MS for drug discovery of Alzheimer's treatment

Trends in Research (2018), DOI:10.15761/TR.1000113

  • Zenzaburo Tozuka 1,2,3
  • Akihiro Kunisawa 2
  • Fumiyuki Shirai 3,4
  • Yoshinori Ishii 3,4
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2018.07

Multi omics by LC-MS/MS to search small molecule ligands of nuclear receptors to control transcription of pharmaceutical active proteins for drug discovery

Trends in Research (2018), DOI: 10.15761/TR.1000111

  • Zenzaburo Tozuka 1
  • Akihiro Kunisawa 1
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2018.01

Free D-amino acids produced by commensal bacteria in the colonic lumen

Scientific Reports (2018), DOI:10.1038/s41598-018-36244-z

  • Mitsuharu Matsumoto 1
  • Akihiro Kunisawa 2,3
  • Takanari Hattori 2,3
  • Shuichi Kawana 2
  • Yusuke Kitada 1
  • Hazuki Tamada 1
  • Shinichi Kawano 2,3
  • Yoshihiro Hayakawa 2
  • Junko Iida 2,3
  • Eiichiro Fukusaki 3,4
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2016.6

GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to 13C-metabolic flux analysis of Escherichia coli central metabolism

Analytical and Bioanalytical Chemistry, June, 2016, in press.

  • Nobuyuki Okahashi 1
  • Shuichi Kawana 2
  • Junko Iida 2,3
  • Hiroshi Shimizu 1
  • Fumio Matsuda 1
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