SPM-Nanoa - Applications

Scanning Probe Microscope/Atomic Force Microscope

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Application Software

Application software for a wide variety of samples, from soft to hard materials, can provide powerful help for observing what you want to observe.

Hard Materials ・Nanoparticles　・Nanofibers　・Fillers　・Ceramics　・Metals
Soft Materials ・Plastics　・Rubbers　・Films　・Biological materials　・Composite materials
Life Sciences and Healthcare ・Lipid membranes　・Cells　・Biological molecules　・Hair
Electronics ・Battery materials　・Semiconductors　・Recording media

What do you want to observe?

What do you want to observe?

* Option 

Hard Materials

Silica Nanoparticles

Silica Nanoparticles

Observation of silica nanoparticles confirmed uniformity of nanoparticle sizes.

Life Sciences and Healthcare

Extracellular Vesicles

Extracellular Vesicles

The large particles shown in the center are extracellular vesicles. With the ability to not only observe shapes, but also evaluate mechanical properties, the system is expected to be useful for identification and Drug Delivery System (DDS) research for exosomes, liposomes, and typical polymer micellization pathogens, and other applications (using Nano 3D Mapping Fast).

Soft Materials

PVP/CNF Composite Materials

Surface Shape

Surface Shape

Phase

Phase

Surface Shape + Phase

Surface Shape + Phase

 

A water mixture of cellulose nanofiber (CNF) and polyvinylpyrrolidone (PVP) was observed electrospun onto a silicon substrate. The surface shape image shows the cylindrical shape of the fibers and the phase image shows physical property differences of CNF and PVP fibers as differences in contrast.
(Sample source: Professor Nakai, Graduate School & Faculty of Bioresources, Mie University)

Lipid Membranes

Surface Shape

Surface Shape

Comparison of Approach Force Curve on Lipid Bilayer Membrane vs. Mica

A patch-shaped lipid membrane about 6 nm thick was observed (arrow) near the center of the surface shape image (left). The force curve acquired from on top of the lipid membrane (right) indicates the variations in force generated as the probe penetrated the membrane.

Electronics

Single BaTiO3 Crystal

Surface Shape

Surface Shape

Surface Shape + Amplitude

Phase

Surface Shape + Phase

Surface Shape + Phase

 

BaTiO3, a strong dielectric, was observed using the piezoelectric force mode (PFM).
The amplitude and phase images clearly show the polarized domain structure.