2024

LabSolutions™ MD Support Software for Analytical Method Development for HPLC

Software for Effortless Method Development

LabSolutions MD improves method development efficiency by taking an Analytical Quality by Design (AQbD) approach. This software efficiently develops highly reliable analysis methods by configuring mobile phases, columns, and other parameters using an analysis function that automatically generates analysis schedules with the experimental design method and a data analysis function that plots a design space and predicted chromatogram.
LabSolutions MD enables effortless exploration of optimal conditions through each phase of method development, such as screening and optimization. It enables anyone to easily find optimal conditions without relying on experience.

• More Efficient Condition Searches Using the Experimental Design Method
• Visualizing the Optimal Analysis Conditions
• Integrated Database Management of the Analytical Method Development Process

eMSTAT Solution Statistical Analysis Software

Machine Learning to Support Data Analysis in the Food Sector—A World First—

eMSTAT Solution Ver. 2.0 statistical analysis software  is the first statistical analysis software in the industry for chromatograms to feature machine learning capabilities. The software uses analysis data obtained by a liquid chromatograph (LC), gas chromatograph (GC), and MALDI (matrix-assisted laser desorption/ionization) type mass spectrometer (MS). Since multivariate analysis can be easily performed, differences between target groups can be clarified and shown in comparisons with other products during product development in the food sector or in determining the quality of products during quality control assessments. The software features two modes: a Statistical Analysis Mode for easy visualization of differences and a Discriminant Analysis Mode that identifies unknown samples with models created through machine learning. 

• Statistical Analysis by Intuitive Operations
• Unknown Samples can be discriminated Using Machine-Learning Models
• Even More Convenient Using Related Software

Greenhouse Gas Analyzer Gas Chromatography System

Supporting Carbon-Neutrality Research with Analytical and Measuring Instrument Technologies

 As a specialized gas chromatograph (GC) optimized for measuring greenhouse gases (GHG) caused by climate change, Greenhouse Gas Analyzer can simultaneously measure carbon dioxide (CO₂), methane (CH₄), and nitrous oxide (N₂O), the three components that account for 95 % of GHG. It combines Shimadzu’s high-end Nexis GC-2030 gas chromatograph system with NARO’s patented technology for simultaneously analyzing three GHG components. It is equipped with 3 detectors and columns that ensure reliable simultaneous analysis of the three GHG components. It also supports using small vials as sample containers, in addition to conventional gas bags. It can achieve the high accuracy and process efficiency required for GHG analysis in GX research work.

• Reliably Measuring Three Components from a Single Sample Injection
• Ability to Analyze Multiple Analytes Increases Analytical Efficiency
• User Support Functionality from the Nexis GC-2030 is Included

MUP-3100 Fully Automated Sample Preparation Module for Glycan Analysis

Contributing to the Rapid Development of Pharmaceuticals by Automating Pretreatment in Antibody Glycan Analysis

The  MUP-3100 automates the time-consuming pretreatment process in the analysis of antibody glycans, which is required for the research and development and quality control of antibody pharmaceuticals. A 6-axis robot provides labor savings and increases efficiency with respect to processes that were conventionally performed manually. This enables not only continuous operations, but also eliminates procedural mistakes, ensures the safety of operators, and lessens the burden on them. 
It is expected to be used by pharmaceutical companies as well as contract manufacturing organizations (CMO) and contract development and manufacturing organizations (CDMO), where it will contribute to speeding up the research and development of pharmaceuticals by heightening the safety and efficiency of operations. This instrument is exclusively for antibody glycan analysis using the Auto-EZGlyco™ mAb-N Kit for SHIMADZU from Sumitomo Bakelite Co., Ltd.

• Accurate Repeatability of Pretreatment Processes by a 6-Axis Robot
• Automatic Check Function Supports Stable Operation
• Functions for Enhanced Regulatory Compliance

LCMS-TQ RX Series

Providing More Reliable Data with High Sensitivity and Stability, and Heightening the Efficiency of Laboratory Work with Automatic Calibration

The LCMS-TQ RX series (LCMS-8060RX, LCMS-8050RX, and LCMS-8045RX) triple quadrupole high-performance liquid chromatograph mass spectrometers provide higher sensitivity, stability, and convenient operability. 
With the LCMS-TQ RX series, the data reliability has been heightened by stabling the sample ionization with the ion source improved. This series is equipped with functions that check the instrument status prior to measurements, and automatically implement calibration (tuning), as well as ecology mode for minimizing standby power consumption, thereby achieving high-efficiency laboratory operations with a low environmental impact. Through this series, Shimadzu will heighten the efficiency of laboratory work related to pharmaceuticals, food product development, and environmental inspection so that we contribute to the growth of research and development in healthcare, green transformation, and other sectors.

• Improving data reliability with high stability and measurement sensitivity
• Maintaining favorable instrument conditions, heightening the efficiency of laboratory operations
• Minimization of power consumption by the instrument itself, and reducing load on the lab and the environment

MALDI EasyCare

Increase uptime with Shimadzu’s upgrade option for MALDI-8000 series benchtop linear MALDI-TOF mass spectrometers

The MALDI EasyCare feature enables customers to recover optimal performance by performing instrument maintenance – manual clean of the ion optics and automated tuning of the instrument - thereby reducing engineer call-outs. The entire process is guided by a software wizard resulting in an easy workflow which requires no technical experience. MALDI EasyCare will improve uptime in laboratories and increase analytical productivity on the already successful benchtop MALDI-8000 series, allowing customers to focus on what they do best, which is to produce data for their business.

• Provides access to self-service routine maintenance allowing you to restore performance
• Reduces engineer call-outs, saving time, increasing uptime
• Automated software tuning of deflector and detectors

Nexera™ FV

Ultra High Performance Liquid Chromatograph for Online Dissolution Testing 

The Nexera FV ultra high performance liquid chromatograph (UHPLC) for online analysis is connected directly to a synthesis reactor or dissolution testing machine. After the raw materials or pharmaceutical samples are placed in the peripheral equipment, tasks up to data acquisition by the LC are performed automatically.  With the Nexera FV, samples are automatically injected into the LC from the peripheral equipment via an autosampler (automatic sample injector) equipped with a newly developed flow vial kit.  It can operate continuously without an analyst, enabling continuous sampling and analysis even overnight. Dedicated software (LabSolutions FV) simplifies the setting of sampling timing and analysis mode, as well as the data analysis of the results.

• Reducing Labor Costs and Risks by Automating Synthesis Evaluations
• Provides Labor Savings and Heightened Efficiency in Dissolution Testing
• Dedicated Software Simplifies Operations and Improves Reliability

OAD-TOF System

The world’s first quadrupole time-of-flight mass spectrometer system equipped with ion dissociation technology

The OAD-TOF system, a quadrupole time-of-flight mass spectrometer, is the first in the world to provide detailed structural analyses of lipids and other natural compounds. Oxygen attachment dissociation (OAD), an ion dissociation technology developed by Shimadzu, enables estimation of the position of double bonds between carbon atoms, a conventionally difficult task. In OAD, atomic oxygen is made to react with the ionized sample, and the double bonds between carbon atoms are selectively broken (dissociated). Information on the position of the double bonds between carbon atoms is then obtained from the ion fragments generated by the dissociation. A quadrupole time-of-flight mass spectrometer (Q-TOF MS) measures the size and amount of samples separated at the atomic and molecular levels, thereby obtaining precise information on compounds. In combination, these techniques elucidate the structure of all types of compounds including lipids and other biological compounds. 

• OAD RADICAL SOURCE I, the World’s First Technology to Provide Innovative Structural Analysis
• Switching Quickly and Easily between Two Ion Dissociation Methods
• Accommodating a Variety of Needs through a Wealth of Combinable Options

GCMS-QP2050 Gas Chromatograph Mass Spectrometer

Minimum Maintenance, Maximum Progress​

Explore Shimadzu’s new Single Quadrupole GC-MS, the GCMS-QP2050. It combines the industry's smallest equipment size with impressive durability, offering stable and reliable measurement data that easily meeting the analysis needs of laboratories in a range of industries. The GCMS-QP2050 with the new DuraEase ion source maximizes uptime and sensitivity while requiring minimum maintenance, which can be completed in just a few minutes and a few simple steps. It also supports the efficiency of operations with a variety of user support functions, such as automatic creation of optimal analysis method, and real-time display of equipment start-up and measurement time. ​

• Industry-leading sensitivity and high durability
• Simplified maintenance and AI technology eases task load
• Compact design, the smallest class in the industry, and high expandability

Compact IRSpirit-X Series Fourier Transform Infrared Spectrophotometers

Combining a small instrument size with the highest levels of sensitivity in their class

IRSpirit-X series Fourier Transform Infrared (FTIR) spectrophotometers provide both a small, lightweight design and the highest levels of sensitivity in their class. They are equipped with an analysis navigation program enabling novice FTIR users to obtain data easily, and a function that judges the quality of the measurement results and proposes how to obtain favorable data. 
This series features three models, which can be selected to suit the objective and environment of use: the entry-level IRSpirit-LX, the IRSpirit-TX, which has the highest sensitivity for a small FTIR, and the IRSpirit-ZX, which is capable of stable measurements in high-temperature and high-humidity regions due to more moisture-resistant components. With the IRSpirit-X series of Fourier transform infrared spectrophotometers, Shimadzu realizes an environment in which highly reliable data is more easily obtained. 

• Combines a small, lightweight instrument design with high performance
• Enhanced support functions provide strong support for tasks
• Additional models aimed at high-temperature/high-humidity regions